INCLUSION CRITERIA
You must meet all of the following...
- Female
- Aged 18-75 years
- Resident in greater Seattle metropolitan area (King Country), Pierce or Snohomish Counties
- Healthy
- Able to perform all study requirements, including attendance at clinic visits and capable of responding to questionnaires and clinic and exercise facility instructions in English
- Willing to be assigned by chance by a computer program to either the exercise or control group
- Capable of providing informed consent
EXCLUSION CRITERIA
You cannot participate if any of the following are true...
- Pregnant in past 3 months
- Currently breast feeding
- Current use of any tobacco products including smoking, vaping, chew, nicotine patches
- History of diabetes mellitus or high blood sugar that could indicate diabetes
- Taking any medications to treat high blood sugar such as metformin
- History of any cancer (other than non-melanoma skin cancer)
- Drinking more than 2 alcoholic drinks/day
- Ever told by a doctor that you should NOT exercise
- Findings on the physical exam that could make exercise unsafe
- History of heart attack, stroke, heart failure, heart valve disease, heart rhythm problems, serious lung disease, blood clot in the lungs, uncontrolled high blood pressure
- Frequent marijuana use (more than once per month)
- Alcohol or drug dependence or abuse, or uncontrolled mental illness
- In Premenopausal women:
- irregular periods for the past 6 months
- use of oral contraceptives for the previous 3 months
- use of hormone implants or IUD with hormones (e.g. Mirena) in the previous year
- use of estrogens, progesterone, testosterone or other androgens for the previous 3 months
- In Postmenopausal women:
- use of estrogen, progesterone, testosterone, or other androgens in the previous 3 months, of any type including oral, creams, vaginal creams or inserts, patches, or implants